{"id":1544,"date":"2026-01-16T06:53:21","date_gmt":"2026-01-16T06:53:21","guid":{"rendered":"https:\/\/hiims.in\/hospital\/pune\/?p=1544"},"modified":"2026-02-02T08:17:37","modified_gmt":"2026-02-02T08:17:37","slug":"high-cholesterol-causes-symptoms-treatment","status":"publish","type":"post","link":"https:\/\/hiims.in\/hospital\/pune\/blog\/high-cholesterol-causes-symptoms-treatment","title":{"rendered":"Understanding High Cholesterol : Causes, Symptoms and Treatment"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Cholesterol is a fatty material found in the bloodstream. The body requires it in limited quantity to work well. It helps in making hormones and building cells. But when cholesterol levels rise too much, it becomes a health problem. Many people live with high cholesterol without knowing it. This is because the problem grows slowly and usually does not cause pain in the beginning.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">People often ask about <\/span><a href=\"https:\/\/hiims.in\/hospital\/pune\/cholesterol\"><b>cholesterol causes<\/b><\/a><span style=\"font-weight: 400;\"> because the condition is common today. Long sitting hours, outside food, stress, and lack of exercise are some reasons. Sometimes, family history also plays a role. When cholesterol stays high for a long time, it can block blood flow and affect the heart. So it is better to understand the signs early and take care on time.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In this article, we explain what high cholesterol is, its symptoms, reasons, and how it can be managed with simple habits and Ayurvedic care.<\/span><\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/hiims.in\/hospital\/pune\/blog\/high-cholesterol-causes-symptoms-treatment\/#Key_Symptoms_of_High_Cholesterol\" >Key Symptoms of High Cholesterol<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/hiims.in\/hospital\/pune\/blog\/high-cholesterol-causes-symptoms-treatment\/#Main_Causes_of_High_Cholesterol\" >Main Causes of High Cholesterol<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/hiims.in\/hospital\/pune\/blog\/high-cholesterol-causes-symptoms-treatment\/#Ayurvedic_Approach_for_High_Cholesterol_Treatment\" >Ayurvedic Approach for High Cholesterol Treatment<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/hiims.in\/hospital\/pune\/blog\/high-cholesterol-causes-symptoms-treatment\/#Natural_Ways_to_Control_Cholesterol\" >Natural Ways to Control Cholesterol<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/hiims.in\/hospital\/pune\/blog\/high-cholesterol-causes-symptoms-treatment\/#Other_Health_Conditions_We_Also_Treat\" >Other Health Conditions We Also Treat<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/hiims.in\/hospital\/pune\/blog\/high-cholesterol-causes-symptoms-treatment\/#Prevention_Tips_for_High_Cholesterol\" >Prevention Tips for High Cholesterol<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/hiims.in\/hospital\/pune\/blog\/high-cholesterol-causes-symptoms-treatment\/#Conclusion\" >Conclusion<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/hiims.in\/hospital\/pune\/blog\/high-cholesterol-causes-symptoms-treatment\/#FAQs\" >FAQs<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Key_Symptoms_of_High_Cholesterol\"><\/span><strong>Key Symptoms of High Cholesterol<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">High cholesterol does not always show clear signs. Many people feel normal for years. Still, the body gives some small signals, which are often ignored.<\/span><\/p>\n<p>You may notice:<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Feeling tired often without reason<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mild chest discomfort after walking or climbing stairs<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Breathlessness during small physical work<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pain or heaviness in chest or arms sometimes<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Yellowish patches around eyes in some cases<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These high cholesterol symptoms do not come suddenly. They develop slowly. That is why people miss them or think it is just age or stress.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When cholesterol blocks blood vessels, it affects the heart and brain. This can increase the risk of heart attack or stroke. So noticing early symptoms and checking lipid levels is important.<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Main_Causes_of_High_Cholesterol\"><\/span><strong>Main Causes of High Cholesterol<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Understanding the causes of high cholesterol helps in prevention. Many reasons are linked to daily habits.<\/span><\/p>\n<p>Common cholesterol causes include:<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Eating fried, oily, and packaged food often<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Excess intake of sweets and bakery items<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sitting for long hours without movement<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lack of exercise or physical work<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Family history of cholesterol problems<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stress and disturbed sleep routine<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Sometimes cholesterol rises even if food intake is less. This happens due to slow digestion or poor metabolism. Hormonal imbalance and age also increase the risk.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Small changes in routine can reduce cholesterol risk. Starting care early is always better than dealing with major problems later.<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Ayurvedic_Approach_for_High_Cholesterol_Treatment\"><\/span><strong>Ayurvedic Approach for High Cholesterol Treatment<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">In Ayurveda, cholesterol is seen as a problem linked with digestion and body metabolism. It focuses on clearing fat buildup and improving digestion slowly.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In Ayurveda, <\/span><b>high cholesterol treatment<\/b><span style=\"font-weight: 400;\"> is managed with herbs that support the heart and vessels. Some remedies often used are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Triphala<\/b><span style=\"font-weight: 400;\"> \u2013 helps digestion and keeps fat under control<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Guggul<\/b><span style=\"font-weight: 400;\"> \u2013 slowly works on bad cholesterol<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Arjuna bark<\/b><span style=\"font-weight: 400;\"> \u2013 supports heart strength<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Methi seeds<\/b><span style=\"font-weight: 400;\"> \u2013 reduce fat getting absorbed<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Garlic<\/b><span style=\"font-weight: 400;\"> \u2013 helps blood flow stay smooth<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Ayurveda follows a slow and steady method. Remedies are selected based on body nature. The focus stays on balance, not quick results.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">At Jeena Sikho HiiMS, doctors check digestion, lifestyle, stress, and routine before planning care. Treatment is slow but steady.<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Natural_Ways_to_Control_Cholesterol\"><\/span><strong>Natural Ways to Control Cholesterol<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Lifestyle plays a big role in cholesterol control. Medicines alone are not enough.<\/span><\/p>\n<p>Simple habits that help:<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Eat more fruits, vegetables, and millets<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Avoid fried and packaged food<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drink warm water during the day<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Eat meals on time and avoid late nights<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Walk daily or do light exercise<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Practice yoga and breathing exercises<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">When these habits are followed, digestion improves slowly. Stress also reduces, and that helps keep cholesterol under control.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Small steps, when followed daily, give good results over time.<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Other_Health_Conditions_We_Also_Treat\"><\/span><strong>Other Health Conditions We Also Treat<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Cholesterol problems often come with other health issues. So overall care is very important.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Doctors at Jeena Sikho HiiMS do not handle only one illness. They also handle health problems like cancer, liver issues, heart disease, infertility, jaundice, and many long-term conditions. Treatment focuses on the whole body, not just one disease.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When the body is treated as a whole, recovery becomes smoother. Patients feel better energy, digestion improves, and mental stress reduces.<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Prevention_Tips_for_High_Cholesterol\"><\/span><strong>Prevention Tips for High Cholesterol<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Prevention is always better than cure. Cholesterol can be controlled if care starts early.<\/span><\/p>\n<p>Helpful prevention tips:<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Avoid outside food as much as possible<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cook food with less oil and spices<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sleep on time and wake up early<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Manage stress through walking or meditation<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Check cholesterol levels regularly<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Following these habits reduces the risk of heart problems. Timely and small care today helps in preventing serious health issues in the future.<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Conclusion\"><\/span><strong>Conclusion<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">High cholesterol is a silent problem. It grows slowly and often shows no warning signs. Understanding cholesterol causes and noticing early <\/span><b>high cholesterol symptoms<\/b><span style=\"font-weight: 400;\"> is important. Signs like tiredness, chest discomfort, or breathlessness should not be ignored.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ayurveda offers natural support through diet, herbs, detox, and routine correction. High cholesterol treatment works better when lifestyle changes are followed along with it. At <\/span><a href=\"https:\/\/hiims.in\/hospital\/pune\/\"><b>Jeena Sikho HiiMS<\/b><\/a><span style=\"font-weight: 400;\">, care is planned carefully, keeping the patient\u2019s daily life in mind.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you have a family history or notice symptoms, it is better to consult early. Do not wait for problems to increase. Take a small step today for a healthier heart and better life.<\/span><\/p>\n<p><a href=\"https:\/\/hiims.in\/hospital\/pune\/book-an-appointment\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1468\" src=\"https:\/\/hiims.in\/hospital\/pune\/wp-content\/uploads\/sites\/23\/2025\/11\/book-appointment-300x91.png\" alt=\"book an appointment at Jeena Sikho Hiims\" width=\"300\" height=\"91\" srcset=\"https:\/\/hiims.in\/hospital\/pune\/wp-content\/uploads\/sites\/23\/2025\/11\/book-appointment-300x91.png 300w, https:\/\/hiims.in\/hospital\/pune\/wp-content\/uploads\/sites\/23\/2025\/11\/book-appointment-1024x310.png 1024w, https:\/\/hiims.in\/hospital\/pune\/wp-content\/uploads\/sites\/23\/2025\/11\/book-appointment-768x232.png 768w, https:\/\/hiims.in\/hospital\/pune\/wp-content\/uploads\/sites\/23\/2025\/11\/book-appointment-1536x465.png 1536w, https:\/\/hiims.in\/hospital\/pune\/wp-content\/uploads\/sites\/23\/2025\/11\/book-appointment.png 1791w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<h2><span class=\"ez-toc-section\" id=\"FAQs\"><\/span>FAQs<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><strong>Q1. What are common symptoms of high cholesterol?<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">Tiredness, chest discomfort, breathlessness, and heart strain.<\/span><\/p>\n<h3><strong>Q2. What causes cholesterol to increase?<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">Oily food, stress, lack of exercise, and family history.<\/span><\/p>\n<h3><strong>Q3. Can Ayurveda help in cholesterol control?<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">Yes, it improves digestion and reduces fat naturally.<\/span><\/p>\n<h3><strong>Q4. Is high cholesterol dangerous?<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">If untreated, it increases heart and stroke risk.<\/span><\/p>\n<h3><strong>Q5. When should cholesterol be checked?<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">Adults should check regularly, especially with family history.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cholesterol is a fatty material found in the bloodstream. The body requires it in limited quantity to work well. It [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1546,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[43],"tags":[36,35,37,38],"class_list":["post-1544","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cholesterol","tag-causes-of-high-cholesterol","tag-cholesterol-causes","tag-high-cholesterol-symptoms","tag-high-cholesterol-treatment"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>High Cholesterol: Causes, Symptoms and Treatment<\/title>\n<meta name=\"description\" content=\"Learn about high cholesterol, its causes, symptoms, and treatment. 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